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INFORMATION ON VITAMIN B12 (METHYLCOBALAMIN)
Vitamin B12 is a water-soluble vitamin that functions as a coenzyme in methylation reactions and energy metabolism. Its active forms are methylcobalamin and adenosylcobalamin, both essential for DNA synthesis, fatty acid metabolism, and neurological function.
Functions:
- Works with folate and B6 in homocysteine metabolism
- Supports red blood cell formation and DNA synthesis
- Essential for neurological function and myelin maintenance
- Participates in energy production via conversion of methylmalonyl-CoA to succinyl-CoA
TAILORBLEND uses methylcobalamin for superior bioavailability, neurological support, and methylation efficiency.
POPULAR USE & PUBLISHED BENEFITS bbbb
Vitamin B12 is commonly used to support:
- Red blood cell formation and prevention of megaloblastic anemia
- Nervous system health, including myelin formation and cognitive function
- Energy production and reduction of fatigue
- Mood regulation and neurotransmitter synthesis (serotonin, dopamine)
- Cardiovascular health via homocysteine metabolism
- Supports elderly and vegan populations who are at higher risk of deficiency
WHOLE FOODS
Animal Sources:
- Beef liver, clams, fish (salmon, tuna, sardines), eggs, dairy
Plant-Based Sources:
- Naturally absent
RECOMMENDED USE
Synergistic Nutrients:
- Folate (5-MTHF): Works with B12 in methylation and red blood cell production
- B6: Supports homocysteine metabolism
- Choline & betaine: Support methylation pathways
Typical Dosages:
- Maintenance: 2.4 µg/day (adults)
- Functional support (energy, mild deficiency): 30–150 µg/day
- Therapeutic (neuropathy, pernicious anemia, B12 deficiency): 100–1000 µg/day orally
- Generally safe with low toxicity
- High-dose supplementation may interact with certain medications (e.g., chloramphenicol, proton pump inhibitors, metformin)
- Individuals with pernicious anemia or intrinsic factor deficiency require medical supervision for injections
- Monitor B12 levels if supplementing long-term, especially in elderly or vegan populations
VITAMIN B12 (METHYLCOBALAMIN)
- NIH Fact Sheet on Vitamin B12: ods.od.nih.gov
- Linus Pauling Institute: lpi.oregonstate.edu
- Stabler SP. N Engl J Med (2013) – Vitamin B12 deficiency
- Kennedy DO. Nutrients (2016) – B12 and cognitive function
- Green R. Blood (2017) – B12 metabolism and clinical applications