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INFORMATION ON VITAMIN B5 (CA-D-PANTOTHENATE)
Vitamin B5 is a precursor to Coenzyme A (CoA) and acyl carrier protein, both critical for energy metabolism and fatty acid synthesis.
Functions:
- Enables Krebs cycle energy production
- Essential for acetyl-CoA formation (key in neurotransmitters, hormones, cholesterol)
- Involved in synthesis of steroid hormones (cortisol, testosterone, estrogen)
- Supports healthy wound healing and tissue repair
POPULAR USE & PUBLISHED BENEFITS bbbb
Pantothenic acid is commonly used to support:
- Energy production from fats, proteins, and carbohydrates
- Stress resilience and adrenal function (“anti-stress vitamin”)
- Healthy skin, hair, and wound healing
- Cholesterol and steroid hormone synthesis
- Nervous system and mental performance
- Red blood cell formation
WHOLE FOODS
Animal Sources:
- Liver, kidney, chicken, beef, eggs, salmon, shellfish
Plant-Based Sources:
- Sunflower seeds, avocados, mushrooms, sweet potatoes, lentils, broccoli, whole grains
RECOMMENDED USE
Synergistic Nutrients:
- Vitamin C: Works with B5 in adrenal hormone production
- B6 + B12: Complement energy and neurotransmitter metabolism
- CoQ10 & L-carnitine: Work in synergy with CoA pathways
Typical Dosages:
- Maintenance: 5–10 mg/day
- Functional support: 50–100 mg/day
- Therapeutic (acne, stress, adrenal support): 250–500 mg/day (pantethine often used at 300–900 mg/day in studies)
- Very well tolerated, even at high doses
- Rare side effects: mild GI upset, diarrhea at doses >1–2 g/day
- Deficiency is rare but may cause fatigue, irritability, numbness, and “burning feet” syndrome
VITAMIN B5 (CA-D-PANTOTHENATE)
- NIH Fact Sheet on Pantothenic Acid: ods.od.nih.gov
- Linus Pauling Institute: lpi.oregonstate.edu
- Heird WC et al. Am J Clin Nutr (1983) – Pantothenic acid deficiency in humans
- Hafez E et al. Dermatol Ther (2012) – Pantothenic acid in acne management
- Fry PC et al. Am J Clin Nutr (1976) – Metabolism and adrenal steroid synthesis