INFORMATION ON L-CITRULLINE MALATE

L-citrulline malate is a salt form of the amino acid L-citrulline, with malic acid (or malate) enhancing the effects of citrulline.

L-citrulline, L-arginine and L-Ornithine are the three dietary amino acids in the urea cycle, where toxic ammonia (waste from protein digestion) is converted into uric acid/urea and removed from the body.

L-citrulline is a naturally occuring amino acid and as a byproduct of arginine and ornithine, improves blood flow and cardiovascular health. Less restrictive blood flow could heighten endurance levels and naturally increase energy levels. It has also been shown highly effective in the production of growth hormone, insulin and creatine, responsible for metabolic processes and signalling (chemical messaging).

As an important agent in the Krebs cycle, malic acid stimulates metabolism and increases energy production. It helps to improve overall muscle performance, reduce tiredness and low energy levels, reverse muscle fatigue and improve mental clarity.

Citrulline is thought to be a pro-erectile agent and is used to assist with sexual dysfunction.

Studies on L-citrulline malate demonstrated reduction in mental and physical fatigue and exhaustion in geriatric and post-surgery patients.

How it works:

L-citrulline is produced via two pathways: arginine metabolism (nitric oxide cycle) and ornithine metabolism (urea cycle), which means supplementation with L-citrulline also increases ornithine and arginine plasma levels.

It helps to increase nitric oxide production, improves the removal of ammonia and improves the efficacy of the Krebs cycle.

Research suggests that by assisting protein metabolism, minimising amino acid breakdown and eliminating ammonia and lactic acid from the blood, L-citrulline malate can supply sustained energy, boost athletic performance and enhance recovery.