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INFORMATION ON VITAMIN D3 (CHOLECALCIFEROL)
Vitamin D is a fat-soluble vitamin that acts as a hormone precursor, converted in the liver to 25-hydroxyvitamin D (25(OH)D) and in the kidney to the active form 1,25-dihydroxyvitamin D (calcitriol).
Functions:
- Regulates calcium and phosphorus absorption and homeostasis
- Supports bone mineralization and skeletal integrity
- Modulates immune system activity and inflammation
- Influences gene expression and cell differentiation
TAILORBLEND typically uses vitamin D3 (cholecalciferol) for superior potency and sustained serum levels compared to D2.
POPULAR USE & PUBLISHED BENEFITS bbbb
Vitamin D is commonly used to support:
- Bone health and calcium/phosphorus balance
- Muscle function and strength
- Immune system modulation and infection defense
- Mood regulation and mental health (including seasonal mood support)
- Cardiovascular health
- Anti-inflammatory and cellular signaling functions
WHOLE FOODS
Animal Sources:
- Fatty fish (salmon, mackerel, sardines), cod liver oil, eggs, liver, fortified dairy
Plant-Based Sources:
- Fortified plant milks, fortified cereals, UV-exposed mushrooms
RECOMMENDED USE
Synergistic Nutrients:
- Vitamin K2: Supports calcium deposition in bones, prevents vascular calcification
- Magnesium: Required for vitamin D metabolism and activation
- Calcium: Works with vitamin D for bone health
Typical Dosages:
- Maintenance: 600–800 IU/day (15–20 µg/day)
- Functional support (bone, immunity, mood): 1000–4000 IU/day (25–100 µg/day)
- Therapeutic (deficiency correction): 5000–10,000 IU/day short-term under supervision
- Upper safe limit: 4000 IU/day for adults (long-term)
- Excess vitamin D can cause hypercalcemia, kidney stones, and soft tissue calcification
- Monitor serum 25(OH)D and calcium if supplementing high doses
- Individuals with sarcoidosis, kidney disease, or hyperparathyroidism require medical supervision
VITAMIN D3 (CHOLECALCIFEROL)
- NIH Fact Sheet on Vitamin D: ods.od.nih.gov
- Linus Pauling Institute: lpi.oregonstate.edu
- Holick MF. N Engl J Med (2007) – Vitamin D deficiency and health
- Martineau AR et al. BMJ (2017) – Vitamin D supplementation and respiratory infections
- Bouillon R et al. Endocr Rev (2019) – Vitamin D metabolism and clinical use